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CMap Candidate Details

Structure:
CMap ID: C04156
Pert ID: BRD-K13094524
Compound Name: PFI-1
Targets: BRD4
MoA: bromodomain inhibitor
SMILES: COc1ccccc1S(=O)(=O)Nc1ccc2NC(=O)N(C)Cc2c1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
90896 BRD-K13094524 MCF10A 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
93613 BRD-K13094524 A549 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93649 BRD-K13094524 ASC 10 uM 24 h 0.0 0.0 0.0 -0.38 -1.28 1.45
93708 BRD-K13094524 CD34 10 uM 24 h 0.3 1.25 0.53 -0.34 -1.13 1.0
93754 BRD-K13094524 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93789 BRD-K13094524 HCC515 10 uM 24 h 0.0 0.0 0.0 0.31 1.1 0.68
93835 BRD-K13094524 HEK293 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93882 BRD-K13094524 HELA 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93957 BRD-K13094524 HUVEC 10 uM 24 h 0.29 1.21 0.47 -0.37 -1.24 1.35
94019 BRD-K13094524 JURKAT 10 uM 24 h 0.23 0.97 0.08 -0.24 -0.8 0.12
94059 BRD-K13094524 MCF??7.00 3.33 uM 24 h 0.0 0.0 0.0 -0.33 -1.1 0.87
94157 BRD-K13094524 NPC 10 uM 24 h -0.24 -0.99 0.14 -0.35 -1.16 1.11
94233 BRD-K13094524 SHSY5Y 10 uM 24 h 0.0 0.0 0.0 0.22 0.79 0.07
94284 BRD-K13094524 SKL 10 uM 24 h 0.0 0.0 0.0 -0.31 -1.03 0.63
94333 BRD-K13094524 THP1 10 uM 24 h 0.0 0.0 0.0 -0.25 -0.84 0.17
94377 BRD-K13094524 YAPC 3.33 uM 24 h 0.3 1.25 0.56 0.0 0.0 0.0
118684 BRD-K13094524 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
118834 BRD-K13094524 HEPG2 10 uM 24 h 0.0 0.0 0.0 -0.33 -1.12 0.93
118876 BRD-K13094524 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
118951 BRD-K13094524 PC3 0.12 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).