CMap Candidate Details
Structure:
| CMap ID: | C04179 |
| Pert ID: | BRD-K11399644 |
| Compound Name: | phenformin |
| Targets: | KCNJ8|PRKAA1 |
| MoA: | AMPK activator |
| SMILES: | NC(=N)NC(=N)NCCc1ccccc1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 4545 | BRD-K11399644 | HCC515 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 39629 | BRD-K11399644 | ASC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 40752 | BRD-K11399644 | NEU | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 41052 | BRD-K11399644 | NPC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.25 | -0.85 | 0.19 |
| 41381 | BRD-K11399644 | SKB | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.33 | -1.12 | 0.93 |
| 52856 | BRD-K11399644 | HEPG2 | 40 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.33 | -1.11 | 0.9 |
| 53068 | BRD-K11399644 | MCF10A | 30 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 88135 | BRD-K11399644 | VCAP | 30 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.3 | -0.99 | 0.51 |
| 121173 | BRD-K11399644 | A375 | 3.33 uM | 24 h | 0.22 | 0.9 | 0.02 | 0.0 | 0.0 | 0.0 |
| 121208 | BRD-K11399644 | A549 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.25 | 0.87 | 0.17 |
| 121242 | BRD-K11399644 | HA1E | 0.04 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121260 | BRD-K11399644 | HELA | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121283 | BRD-K11399644 | HT29 | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121335 | BRD-K11399644 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.35 | -1.17 | 1.12 |
| 121355 | BRD-K11399644 | YAPC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129349 | BRD-K11399644 | MCF??7.00 | 0.74 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.42 | -1.4 | 2.02 |