CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C04188
Pert ID:	BRD-A67799922
Compound Name:	phenoxybenzamine
Targets:	ADRA1A\|ADRA1B\|ADRA1D\|ADRA2A\|ADRA2B\|ADRA2C\|ADRB2\|CALM1
MoA:	adrenergic receptor antagonist
SMILES:	CC(COc1ccccc1)N(CCCl)Cc1ccccc1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
4024	BRD-A67799922	HA1E	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
4759	BRD-A67799922	PC3	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
5005	BRD-A67799922	VCAP	10 uM	6 h	0.28	1.16	0.34	-0.27	-0.91	0.3
37095	BRD-A67799922	A375	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
37247	BRD-A67799922	A549	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
37534	BRD-A67799922	ASC	10 uM	24 h	-0.25	-1.03	0.19	0.0	0.0	0.0
37842	BRD-A67799922	HEPG2	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
38031	BRD-A67799922	HT29	10 uM	6 h	0.0	0.0	0.0	-0.24	-0.82	0.15
38263	BRD-A67799922	MCF??7.00	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
38381	BRD-A67799922	NPC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
50308	BRD-A67799922	HCC515	10 uM	6 h	0.0	0.0	0.0	-0.39	-1.3	1.67
91071	BRD-A67799922	HUH7	10 uM	72 h	0.21	0.88	0.01	0.0	0.0	0.0

Summary