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CMap Candidate Details

Structure:
CMap ID: C04199
Pert ID: BRD-K10843433
Compound Name: phenylbutazone
Targets: PTGIS|PTGS1|PTGS2
MoA: cyclooxygenase inhibitor; prostanoid receptor antagonist
SMILES: CCCCC1C(=O)N(N(C1=O)c1ccccc1)c1ccccc1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2836 BRD-K10843433 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3141 BRD-K10843433 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3942 BRD-K10843433 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44671 BRD-K10843433 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44852 BRD-K10843433 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
45967 BRD-K10843433 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46287 BRD-K10843433 PHH 10 uM 24 h 0.24 0.99 0.1 0.0 0.0 0.0
46603 BRD-K10843433 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
52267 BRD-K10843433 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
91339 BRD-K10843433 HUH7 10 uM 72 h 0.22 0.9 0.03 -0.26 -0.89 0.26
100071 BRD-K10843433 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
121158 BRD-K10843433 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129266 BRD-K10843433 HELA 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129307 BRD-K10843433 HT29 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129342 BRD-K10843433 MCF??7.00 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129379 BRD-K10843433 YAPC 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).