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CMap Candidate Details

Structure:
CMap ID: C04201
Pert ID: BRD-K73381542
Compound Name: phenylephrine
Targets: ADRA1A|ADRA1B|ADRA1D
MoA: adrenergic receptor agonist
SMILES: CNC[C@H](O)c1cccc(O)c1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
53043 BRD-K73381542 HEPG2 12 uM 48 h 0.26 1.09 0.23 0.19 0.69 0.01
99446 BRD-K73381542 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
127374 BRD-K73381542 A375 0.04 uM 24 h 0.24 1.0 0.11 0.0 0.0 0.0
127451 BRD-K73381542 HA1E 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127479 BRD-K73381542 HELA 3.33 uM 24 h 0.0 0.0 0.0 0.35 1.23 1.19
127542 BRD-K73381542 JURKAT 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127629 BRD-K73381542 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127715 BRD-K73381542 YAPC 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135354 BRD-K73381542 A549 2.22 uM 24 h 0.0 0.0 0.0 -0.28 -0.94 0.38
135421 BRD-K73381542 HT29 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135455 BRD-K73381542 MCF10A 0.01 uM 24 h -0.27 -1.12 0.39 -0.24 -0.82 0.14
135485 BRD-K73381542 MCF??7.00 2.22 uM 24 h -0.29 -1.22 0.61 0.0 0.0 0.0
135511 BRD-K73381542 THP1 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).