CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C04219
Pert ID:	BRD-K25650355
Compound Name:	physostigmine-salicylate
Targets:
MoA:	acetylcholinesterase inhibitor
SMILES:	CNC(=O)Oc1ccc2N(C)[C@H]3N(C)CC[C@@]3(C)c2c1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
5440	BRD-K25650355	HA1E	10 uM	6 h	-0.24	-0.98	0.13	0.0	0.0	0.0
5600	BRD-K25650355	HCC515	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
6532	BRD-K25650355	VCAP	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
37371	BRD-K25650355	A549	10 uM	6 h	0.0	0.0	0.0	0.27	0.97	0.34
37622	BRD-K25650355	ASC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
37884	BRD-K25650355	HEPG2	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
38450	BRD-K25650355	NPC	10 uM	24 h	0.0	0.0	0.0	-0.22	-0.74	0.05
38931	BRD-K25650355	SKB	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
91128	BRD-K25650355	HUH7	12 uM	72 h	0.0	0.0	0.0	0.0	0.0	0.0
120041	BRD-K25650355	HELA	3.33 uM	24 h	0.0	0.0	0.0	0.31	1.1	0.7
120084	BRD-K25650355	HT29	0.04 uM	24 h	0.0	0.0	0.0	-0.3	-1.01	0.57
120129	BRD-K25650355	MCF??7.00	10 uM	24 h	0.23	0.97	0.08	0.0	0.0	0.0
120171	BRD-K25650355	PC3	0.125 uM	24 h	0.0	0.0	0.0	0.27	0.94	0.29
128789	BRD-K25650355	A375	2.22 uM	24 h	0.0	0.0	0.0	0.29	1.02	0.48
128857	BRD-K25650355	YAPC	0.03 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0

Summary