CMap Candidate Details
Structure:
| CMap ID: | C04238 |
| Pert ID: | BRD-K31792052 |
| Compound Name: | pifithrin-cyclic |
| Targets: | TP53 |
| MoA: | TP53 inhibitor |
| SMILES: | Cc1ccc(cc1)-c1cn2c3CCCCc3sc2n1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 3005 | BRD-K31792052 | HA1E | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.32 | -1.06 | 0.74 |
| 3352 | BRD-K31792052 | HCC515 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 3612 | BRD-K31792052 | PC3 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 3950 | BRD-K31792052 | VCAP | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.21 | -0.7 | 0.03 |
| 44360 | BRD-K31792052 | A375 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.22 | 0.79 | 0.07 |
| 44693 | BRD-K31792052 | A549 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 44918 | BRD-K31792052 | ASC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.25 | 0.88 | 0.18 |
| 45220 | BRD-K31792052 | HEPG2 | 10 uM | 6 h | 0.26 | 1.08 | 0.21 | 0.0 | 0.0 | 0.0 |
| 45489 | BRD-K31792052 | HT29 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 45679 | BRD-K31792052 | MCF??7.00 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.32 | -1.06 | 0.74 |
| 46038 | BRD-K31792052 | NPC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.27 | -0.9 | 0.28 |
| 46354 | BRD-K31792052 | PHH | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.29 | 1.02 | 0.49 |
| 46672 | BRD-K31792052 | SKB | 10 uM | 24 h | -0.23 | -0.98 | 0.11 | 0.0 | 0.0 | 0.0 |
| 99833 | BRD-K31792052 | U2OS | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |