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CMap Candidate Details

Structure:
CMap ID: C04242
Pert ID: BRD-K49371609
Compound Name: PIK-75
Targets: PIK3CA|PIK3CB|PIK3CD|PIK3CG|PRKDC
MoA: DNA protein kinase inhibitor; PI3K inhibitor
SMILES: CN(\N=C\c1cnc2ccc(Br)cn12)S(=O)(=O)c1cc(ccc1C)[N+]([O-])=O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
9052 BRD-K49371609 A375 0.08 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9101 BRD-K49371609 A549 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
9433 BRD-K49371609 AGS 0.08 uM 6 h 0.0 0.0 0.0 0.41 1.45 2.22
10218 BRD-K49371609 HCC515 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
10525 BRD-K49371609 HCT116 0.08 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10793 BRD-K49371609 HEPG2 0.08 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10979 BRD-K49371609 HT29 0.08 uM 24 h 0.0 0.0 0.0 -0.18 -0.59 0.0
11498 BRD-K49371609 NCIH2073 0.08 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11773 BRD-K49371609 NCIH508 0.08 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12059 BRD-K49371609 NCIH596 0.08 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12325 BRD-K49371609 NOMO1 0.08 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12608 BRD-K49371609 PC3 0.08 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12800 BRD-K49371609 SW480 0.08 uM 6 h 0.0 0.0 0.0 -0.22 -0.73 0.05
13283 BRD-K49371609 U937 0.08 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13478 BRD-K49371609 VCAP 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
115360 BRD-K49371609 HA1E 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
115561 BRD-K49371609 MCF??7.00 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).