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CMap Candidate Details

Structure:
CMap ID: C04243
Pert ID: BRD-K29395450
Compound Name: PIK-93
Targets: PI4KB|PIK3C3|PIK3CG
MoA: PI3K inhibitor
SMILES: CC(=O)Nc1nc(C)c(s1)-c1ccc(Cl)c(c1)S(=O)(=O)NCCO
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
91998 BRD-K29395450 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92042 BRD-K29395450 BT20 3.33 uM 3 h 0.0 0.0 0.0 -0.41 -1.38 2.02
92074 BRD-K29395450 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92108 BRD-K29395450 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92142 BRD-K29395450 HS578T 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92194 BRD-K29395450 HT29 10 uM 24 h 0.27 1.15 0.32 -0.32 -1.09 0.84
92238 BRD-K29395450 MCF10A 10 uM 3 h 0.0 0.0 0.0 -0.29 -0.97 0.46
92274 BRD-K29395450 MCF??7.00 10 uM 3 h 0.0 0.0 0.0 0.0 0.0 0.0
92294 BRD-K29395450 MDAMB231 3.33 uM 24 h 0.29 1.2 0.44 0.0 0.0 0.0
92345 BRD-K29395450 PC3 10 uM 24 h 0.2 0.83 0.0 -0.31 -1.05 0.7
92372 BRD-K29395450 SKBR3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).