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CMap Candidate Details

Structure:
CMap ID: C04245
Pert ID: BRD-A85548292
Compound Name: piketoprofen
Targets:
MoA: cyclooxygenase inhibitor
SMILES: CC(C(=O)Nc1cc(C)ccn1)c1cccc(c1)C(=O)c1ccccc1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
125971 BRD-A85548292 A375 10 uM 24 h 0.0 0.0 0.0 0.26 0.93 0.28
126018 BRD-A85548292 HA1E 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126038 BRD-A85548292 HELA 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126152 BRD-A85548292 JURKAT 10 uM 24 h -0.21 -0.87 0.02 0.37 1.31 1.59
126203 BRD-A85548292 MCF10A 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126274 BRD-A85548292 PC3 10 uM 24 h 0.0 0.0 0.0 -0.24 -0.79 0.11
126322 BRD-A85548292 THP1 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134052 BRD-A85548292 A549 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134126 BRD-A85548292 HEK293 2.22 uM 24 h -0.28 -1.19 0.52 0.0 0.0 0.0
134195 BRD-A85548292 HT29 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134214 BRD-A85548292 HUVEC 0.08 uM 24 h 0.31 1.31 0.75 0.26 0.92 0.26
134243 BRD-A85548292 MCF??7.00 0.03 uM 24 h 0.2 0.85 0.01 0.0 0.0 0.0
134275 BRD-A85548292 MDAMB231 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134330 BRD-A85548292 YAPC 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).