CMap Candidate Details
Structure:
| CMap ID: | C04262 |
| Pert ID: | BRD-A69275535 |
| Compound Name: | pinitol |
| Targets: | |
| MoA: | gamma secretase inhibitor |
| SMILES: | COC1C(O)[C@@H](O)C(O)C(O)[C@H]1O |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 126374 | BRD-A69275535 | A549 | 1.11 uM | 24 h | 0.3 | 1.26 | 0.56 | 0.0 | 0.0 | 0.0 |
| 126398 | BRD-A69275535 | HA1E | 0.04 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 126425 | BRD-A69275535 | HEK293 | 3.33 uM | 24 h | 0.36 | 1.48 | 1.12 | 0.36 | 1.28 | 1.37 |
| 126469 | BRD-A69275535 | HELA | 0.04 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 126490 | BRD-A69275535 | HT29 | 0.04 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 126533 | BRD-A69275535 | MCF??7.00 | 0.04 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 126573 | BRD-A69275535 | PC3 | 0.04 uM | 24 h | 0.27 | 1.11 | 0.26 | 0.0 | 0.0 | 0.0 |
| 126594 | BRD-A69275535 | YAPC | 0.04 uM | 24 h | 0.26 | 1.1 | 0.24 | 0.0 | 0.0 | 0.0 |
| 134342 | BRD-A69275535 | A375 | 0.01 uM | 24 h | 0.25 | 1.04 | 0.15 | 0.0 | 0.0 | 0.0 |
| 134492 | BRD-A69275535 | HUVEC | 0.74 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.31 | -1.03 | 0.65 |
| 134533 | BRD-A69275535 | MCF10A | 0.74 uM | 24 h | 0.36 | 1.49 | 1.14 | -0.24 | -0.79 | 0.11 |
| 134591 | BRD-A69275535 | MDAMB231 | 0.01 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |