CMap Candidate Details
Structure:
| CMap ID: | C04281 |
| Pert ID: | BRD-K65992024 |
| Compound Name: | pirenoxine |
| Targets: | |
| MoA: | AGE inhibitor |
| SMILES: | OC(=O)c1cc(O)c2c3nc4ccccc4oc3cc(=O)c2n1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 124581 | BRD-K65992024 | A375 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 124730 | BRD-K65992024 | JURKAT | 3.33 uM | 24 h | -0.23 | -0.98 | 0.12 | 0.29 | 1.04 | 0.56 |
| 124765 | BRD-K65992024 | MCF??7.00 | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 124846 | BRD-K65992024 | PC3 | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 124888 | BRD-K65992024 | THP1 | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 132695 | BRD-K65992024 | A549 | 0.25 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 132725 | BRD-K65992024 | HA1E | 0.74 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.22 | 0.79 | 0.08 |
| 132761 | BRD-K65992024 | HEK293 | 2.22 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.3 | -1.0 | 0.52 |
| 132792 | BRD-K65992024 | HELA | 0.25 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 132814 | BRD-K65992024 | HT29 | 0.25 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 132877 | BRD-K65992024 | MCF10A | 0.25 uM | 24 h | -0.35 | -1.44 | 1.43 | 0.0 | 0.0 | 0.0 |
| 132919 | BRD-K65992024 | MDAMB231 | 0.74 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.2 | 0.72 | 0.03 |
| 132959 | BRD-K65992024 | YAPC | 2.22 uM | 24 h | -0.28 | -1.16 | 0.47 | 0.0 | 0.0 | 0.0 |