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CMap Candidate Details

Structure:
CMap ID: C04285
Pert ID: BRD-K96862998
Compound Name: pirfenidone
Targets: FURIN|TNF
MoA: TGF beta receptor inhibitor
SMILES: Cc1ccc(=O)n(c1)-c1ccccc1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2151 BRD-K96862998 HCC515 10 uM 6 h 0.0 0.0 0.0 -0.29 -0.98 0.49
2495 BRD-K96862998 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39537 BRD-K96862998 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39863 BRD-K96862998 ASC 10 uM 24 h 0.0 0.0 0.0 -0.32 -1.07 0.78
40957 BRD-K96862998 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41283 BRD-K96862998 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41625 BRD-K96862998 SKB 10 uM 24 h 0.0 0.0 0.0 -0.43 -1.44 15.35
128455 BRD-K96862998 HEK293 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128513 BRD-K96862998 HT29 0.37 uM 24 h 0.0 0.0 0.0 -0.2 -0.68 0.02
128565 BRD-K96862998 JURKAT 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128602 BRD-K96862998 MCF10A 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128657 BRD-K96862998 MDAMB231 10 uM 24 h 0.28 1.16 0.36 0.0 0.0 0.0
128690 BRD-K96862998 PC3 10 uM 24 h -0.34 -1.41 1.26 0.0 0.0 0.0
128737 BRD-K96862998 THP1 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
136194 BRD-K96862998 A375 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
136239 BRD-K96862998 HA1E 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
136273 BRD-K96862998 HELA 0.08 uM 24 h 0.18 0.74 0.0 -0.34 -1.14 1.03
136351 BRD-K96862998 MCF??7.00 0.03 uM 24 h 0.27 1.11 0.25 0.3 1.05 0.58
136391 BRD-K96862998 YAPC 0.08 uM 24 h 0.0 0.0 0.0 0.25 0.89 0.2
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).