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CMap Candidate Details

Structure:
CMap ID: C04306
Pert ID: BRD-K11853856
Compound Name: PJ-34
Targets: EEF2|PARP1|PARP15|PARP3
MoA: PARP inhibitor
SMILES: CN(C)CC(=O)Nc1ccc2[nH]c(=O)c3ccccc3c2c1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1177 BRD-K11853856 PC3 10 uM 24 h 0.0 0.0 0.0 -0.38 -1.27 1.39
1264 BRD-K11853856 A549 10 uM 6 h 0.0 0.0 0.0 -0.19 -0.62 0.0
1306 BRD-K11853856 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
1397 BRD-K11853856 U2OS 10 uM 6 h -0.2 -0.85 0.01 -0.41 -1.38 2.02
8912 BRD-K11853856 A375 10 uM 24 h -0.21 -0.89 0.04 0.0 0.0 0.0
9363 BRD-K11853856 AGS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9670 BRD-K11853856 H1299 10 uM 6 h 0.0 0.0 0.0 -0.35 -1.17 1.13
9872 BRD-K11853856 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
10110 BRD-K11853856 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
10464 BRD-K11853856 HCT116 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10734 BRD-K11853856 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10946 BRD-K11853856 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
11422 BRD-K11853856 NCIH2073 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11713 BRD-K11853856 NCIH508 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11990 BRD-K11853856 NCIH596 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12734 BRD-K11853856 SW480 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13213 BRD-K11853856 U937 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13583 BRD-K11853856 VCAP 10 uM 6 h 0.0 0.0 0.0 -0.26 -0.88 0.25
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).