CMap Candidate Details
Structure:
| CMap ID: | C04311 |
| Pert ID: | BRD-A28467416 |
| Compound Name: | PKI-179 |
| Targets: | MTOR |
| MoA: | mTOR inhibitor; PI3K inhibitor |
| SMILES: | O=C(Nc1ccncc1)Nc1ccc(cc1)-c1nc(nc(n1)N1CCOCC1)N1C2CCC1COC2 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 119985 | BRD-A28467416 | A549 | 0.125 uM | 24 h | 0.23 | 0.96 | 0.07 | -0.28 | -0.93 | 0.35 |
| 120071 | BRD-A28467416 | HELA | 10 uM | 3 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 120101 | BRD-A28467416 | HT29 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 120144 | BRD-A28467416 | MCF??7.00 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 120183 | BRD-A28467416 | PC3 | 0.37 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.28 | -0.94 | 0.38 |
| 120215 | BRD-A28467416 | YAPC | 0.37 uM | 24 h | 0.28 | 1.16 | 0.34 | -0.22 | -0.73 | 0.05 |
| 128794 | BRD-A28467416 | A375 | 2.22 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 128811 | BRD-A28467416 | HA1E | 2.22 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |