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CMap Candidate Details

Structure:
CMap ID: C04315
Pert ID: BRD-K99498722
Compound Name: plinabulin
Targets:
MoA: tubulin polymerization inhibitor
SMILES: CC(C)(C)c1[nH]cnc1\C=c1/[nH]c(=O)\c(=C\c2ccccc2)[nH]c1=O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
33683 BRD-K99498722 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
33950 BRD-K99498722 A549 10 uM 6 h 0.25 1.06 0.18 -0.33 -1.1 0.87
34224 BRD-K99498722 ASC 10 uM 24 h 0.0 0.0 0.0 -0.33 -1.12 0.93
34457 BRD-K99498722 HA1E 10 uM 6 h 0.25 1.06 0.19 0.0 0.0 0.0
34726 BRD-K99498722 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
35004 BRD-K99498722 HEPG2 10 uM 6 h -0.24 -1.01 0.16 0.0 0.0 0.0
35238 BRD-K99498722 HT29 10 uM 6 h -0.23 -0.95 0.09 0.0 0.0 0.0
35456 BRD-K99498722 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 -0.32 -1.09 0.82
35648 BRD-K99498722 NEU 10 uM 24 h 0.28 1.17 0.38 0.0 0.0 0.0
35879 BRD-K99498722 NPC 10 uM 24 h -0.26 -1.08 0.29 0.0 0.0 0.0
36018 BRD-K99498722 PC3 10 uM 24 h -0.2 -0.83 0.0 -0.23 -0.77 0.09
36395 BRD-K99498722 PHH 10 uM 24 h 0.19 0.81 0.0 0.0 0.0 0.0
36695 BRD-K99498722 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
36906 BRD-K99498722 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).