CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C04322
Pert ID:	BRD-K71731651
Compound Name:	PNU-120596
Targets:	CHRNA7
MoA:	acetylcholine receptor agonist
SMILES:	COc1cc(OC)c(NC(=O)Nc2cc(C)on2)cc1Cl
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
1614	BRD-K71731651	HA1E	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
1959	BRD-K71731651	HCC515	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
2197	BRD-K71731651	PC3	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
2685	BRD-K71731651	VCAP	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
41834	BRD-K71731651	A375	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
42137	BRD-K71731651	A549	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
42457	BRD-K71731651	ASC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
42768	BRD-K71731651	HEPG2	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
43065	BRD-K71731651	HT29	10 uM	6 h	0.0	0.0	0.0	0.29	1.04	0.55
43230	BRD-K71731651	MCF??7.00	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
43635	BRD-K71731651	NPC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
43934	BRD-K71731651	PHH	10 uM	24 h	0.27	1.13	0.28	0.0	0.0	0.0
44189	BRD-K71731651	SKB	10 uM	24 h	0.31	1.3	0.69	0.0	0.0	0.0
99422	BRD-K71731651	U2OS	10 uM	6 h	0.0	0.0	0.0	-0.17	-0.59	0.0

Summary