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CMap Candidate Details

Structure:
CMap ID: C04325
Pert ID: BRD-K16551401
Compound Name: PNU-22394
Targets: HTR2A|HTR2B|HTR2C|MAOA|MAOB
MoA: serotonin receptor agonist
SMILES: Cn1c2CCNCCc2c2ccccc12
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2988 BRD-K16551401 HA1E 10 uM 6 h 0.28 1.15 0.33 -0.26 -0.89 0.27
3148 BRD-K16551401 HCC515 10 uM 24 h 0.0 0.0 0.0 0.32 1.14 0.85
3598 BRD-K16551401 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
3732 BRD-K16551401 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39095 BRD-K16551401 A375 10 uM 6 h 0.0 0.0 0.0 0.23 0.82 0.1
39301 BRD-K16551401 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39634 BRD-K16551401 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39950 BRD-K16551401 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.29 -0.96 0.43
40232 BRD-K16551401 HT29 10 uM 6 h 0.0 0.0 0.0 -0.22 -0.75 0.06
40593 BRD-K16551401 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.27 0.94 0.3
40758 BRD-K16551401 NEU 10 uM 24 h 0.0 0.0 0.0 -0.28 -0.93 0.34
41058 BRD-K16551401 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41387 BRD-K16551401 SKB 10 uM 24 h 0.0 0.0 0.0 0.28 1.0 0.42
100149 BRD-K16551401 U2OS 10 uM 6 h 0.0 0.0 0.0 0.29 1.04 0.56
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).