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CMap Candidate Details

Structure:
CMap ID: C04345
Pert ID: BRD-K47598052
Compound Name: PP-1
Targets: HCK|RET
MoA: src inhibitor
SMILES: Cc1ccc(cc1)-c1nn(c2ncnc(N)c12)C(C)(C)C
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2888 BRD-K47598052 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3370 BRD-K47598052 HCC515 10 uM 6 h 0.27 1.14 0.31 0.0 0.0 0.0
3514 BRD-K47598052 PC3 10 uM 24 h 0.2 0.84 0.0 -0.3 -1.0 0.55
3813 BRD-K47598052 VCAP 10 uM 24 h 0.0 0.0 0.0 0.24 0.87 0.17
39706 BRD-K47598052 ASC 10 uM 24 h -0.28 -1.18 0.51 0.26 0.93 0.28
40012 BRD-K47598052 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40284 BRD-K47598052 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40477 BRD-K47598052 MCF??7.00 10 uM 24 h 0.21 0.88 0.02 0.0 0.0 0.0
40822 BRD-K47598052 NEU 10 uM 24 h 0.0 0.0 0.0 -0.34 -1.14 1.04
41127 BRD-K47598052 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41462 BRD-K47598052 SKB 10 uM 24 h 0.0 0.0 0.0 -0.33 -1.12 0.97
96148 BRD-K47598052 A549 10 uM 24 h 0.21 0.89 0.02 0.33 1.17 0.92
97332 BRD-K47598052 HAP1 3.33 uM 24 h 0.2 0.82 0.0 0.0 0.0 0.0
97357 BRD-K47598052 A375 3.33 uM 24 h 0.0 0.0 0.0 -0.32 -1.07 0.75
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).