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CMap Candidate Details

Structure:
CMap ID: C04353
Pert ID: BRD-A41304429
Compound Name: practolol
Targets: ADRB1
MoA: adrenergic receptor antagonist
SMILES: CC(C)NCC(O)COc1ccc(NC(C)=O)cc1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5154 BRD-A41304429 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
5263 BRD-A41304429 HA1E 10 uM 24 h 0.18 0.75 0.0 0.31 1.09 0.67
5725 BRD-A41304429 HCC515 10 uM 6 h 0.0 0.0 0.0 -0.23 -0.77 0.09
5980 BRD-A41304429 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6069 BRD-A41304429 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6462 BRD-A41304429 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37234 BRD-A41304429 A549 10 uM 24 h -0.35 -1.45 1.43 -0.28 -0.95 0.39
37496 BRD-A41304429 ASC 10 uM 24 h 0.0 0.0 0.0 -0.36 -1.2 1.17
37819 BRD-A41304429 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
38346 BRD-A41304429 NPC 10 uM 24 h 0.0 0.0 0.0 -0.19 -0.64 0.01
38637 BRD-A41304429 PHH 10 uM 24 h 0.0 0.0 0.0 -0.24 -0.79 0.11
51399 BRD-A41304429 PC3 10 uM 24 h -0.22 -0.9 0.04 0.27 0.96 0.32
91051 BRD-A41304429 HUH7 12.5 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).