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CMap Candidate Details

Structure:
CMap ID: C04367
Pert ID: BRD-A21858158
Compound Name: praziquantel
Targets:
MoA: anthelmintic agent
SMILES: O=C(C1CCCCC1)N1CC2N(CCc3ccccc23)C(=O)C1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5505 BRD-A21858158 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
5829 BRD-A21858158 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.3 -1.01 0.56
6454 BRD-A21858158 VCAP 10 uM 6 h 0.0 0.0 0.0 0.3 1.05 0.57
37216 BRD-A21858158 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37454 BRD-A21858158 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38304 BRD-A21858158 NPC 10 uM 24 h 0.0 0.0 0.0 -0.28 -0.95 0.4
38829 BRD-A21858158 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
91382 BRD-A21858158 HUH7 10 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
121371 BRD-A21858158 A375 10 uM 24 h 0.0 0.0 0.0 -0.24 -0.81 0.13
121415 BRD-A21858158 HELA 0.04 uM 24 h 0.0 0.0 0.0 0.27 0.95 0.31
121442 BRD-A21858158 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121466 BRD-A21858158 MCF??7.00 0.125 uM 24 h 0.25 1.04 0.16 -0.35 -1.17 1.14
121522 BRD-A21858158 YAPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129441 BRD-A21858158 HA1E 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129559 BRD-A21858158 PC3 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).