CMap Candidate Details
Structure:
CMap ID: | C04368 |
Pert ID: | BRD-K49111258 |
Compound Name: | prazosin |
Targets: | ADRA1A|ADRA1B|ADRA1D|ADRA2A|ADRA2B|ADRA2C|KCNH2|KCNH6|KCNH7 |
MoA: | adrenergic receptor antagonist |
SMILES: | COc1cc2nc(nc(N)c2cc1OC)N1CCN(CC1)C(=O)c1ccco1 |
InchiKey: | |
Compound Aliases: |
Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
---|---|---|---|---|---|---|---|---|---|---|
4118 | BRD-K49111258 | HA1E | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
4440 | BRD-K49111258 | HCC515 | 10 uM | 24 h | -0.19 | -0.78 | 0.0 | 0.0 | 0.0 | 0.0 |
24584 | BRD-K49111258 | A549 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
25378 | BRD-K49111258 | VCAP | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
37678 | BRD-K49111258 | ASC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
37913 | BRD-K49111258 | HEPG2 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
38502 | BRD-K49111258 | NPC | 10 uM | 24 h | -0.2 | -0.85 | 0.01 | -0.26 | -0.88 | 0.25 |
38737 | BRD-K49111258 | PHH | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
52170 | BRD-K49111258 | MCF??7.00 | 10 uM | 6 h | -0.21 | -0.89 | 0.03 | 0.3 | 1.07 | 0.63 |
91013 | BRD-K49111258 | HUH7 | 8 uM | 72 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
99598 | BRD-K49111258 | U2OS | 12.5 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
124571 | BRD-K49111258 | A375 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.25 | -0.84 | 0.18 |
124651 | BRD-K49111258 | HELA | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.36 | -1.21 | 1.24 |
124784 | BRD-K49111258 | MDAMB231 | 0.37 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
124827 | BRD-K49111258 | PC3 | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
124908 | BRD-K49111258 | YAPC | 10 uM | 24 h | 0.26 | 1.1 | 0.24 | 0.35 | 1.22 | 1.15 |
132742 | BRD-K49111258 | HEK293 | 0.01 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
132806 | BRD-K49111258 | HT29 | 0.25 uM | 24 h | -0.23 | -0.96 | 0.1 | 0.0 | 0.0 | 0.0 |
132827 | BRD-K49111258 | JURKAT | 0.08 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
132860 | BRD-K49111258 | MCF10A | 2.22 uM | 24 h | 0.23 | 0.96 | 0.07 | 0.0 | 0.0 | 0.0 |
132926 | BRD-K49111258 | THP1 | 0.03 uM | 24 h | -0.28 | -1.15 | 0.44 | -0.32 | -1.08 | 0.8 |