CMap Candidate Details
Structure:
| CMap ID: | C04369 |
| Pert ID: | BRD-K57304726 |
| Compound Name: | PRE-084 |
| Targets: | SIGMAR1 |
| MoA: | sigma receptor agonist |
| SMILES: | O=C(OCCN1CCOCC1)C1(CCCCC1)c1ccccc1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 5344 | BRD-K57304726 | HA1E | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 5653 | BRD-K57304726 | HCC515 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.32 | -1.09 | 0.82 |
| 5932 | BRD-K57304726 | HEPG2 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.29 | -0.98 | 0.47 |
| 6040 | BRD-K57304726 | HT29 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 6288 | BRD-K57304726 | PC3 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 6573 | BRD-K57304726 | VCAP | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.19 | -0.65 | 0.01 |
| 37177 | BRD-K57304726 | A375 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.37 | 1.31 | 1.59 |
| 37403 | BRD-K57304726 | A549 | 10 uM | 6 h | -0.34 | -1.41 | 1.41 | 0.0 | 0.0 | 0.0 |
| 37700 | BRD-K57304726 | ASC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 38212 | BRD-K57304726 | MCF??7.00 | 10 uM | 24 h | -0.27 | -1.12 | 0.38 | 0.0 | 0.0 | 0.0 |
| 38521 | BRD-K57304726 | NPC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 38978 | BRD-K57304726 | SKB | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 99692 | BRD-K57304726 | U2OS | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.26 | 0.92 | 0.25 |