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CMap Candidate Details

Structure:
CMap ID: C04372
Pert ID: BRD-A27887842
Compound Name: prednisolone
Targets: NR3C1|NR3C2|SERPINA6
MoA: glucocorticoid receptor agonist
SMILES: C[C@]12C[C@H](O)C3C(CCC4=CC(=O)C=C[C@]34C)C1CC[C@]2(O)C(=O)CO
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5149 BRD-A27887842 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
5393 BRD-A27887842 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
5508 BRD-A27887842 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
5977 BRD-A27887842 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6129 BRD-A27887842 PC3 10 uM 24 h -0.23 -0.97 0.11 0.27 0.95 0.31
6439 BRD-A27887842 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37221 BRD-A27887842 A549 10 uM 24 h 0.0 0.0 0.0 -0.25 -0.84 0.18
37467 BRD-A27887842 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37800 BRD-A27887842 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.3 -1.0 0.52
38239 BRD-A27887842 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
38317 BRD-A27887842 NPC 10 uM 24 h -0.25 -1.03 0.19 -0.34 -1.14 1.02
38616 BRD-A27887842 PHH 10 uM 24 h -0.27 -1.13 0.4 0.0 0.0 0.0
38838 BRD-A27887842 SKB 10 uM 24 h 0.0 0.0 0.0 -0.25 -0.85 0.2
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).