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CMap Candidate Details

Structure:
CMap ID: C00438
Pert ID: BRD-K63915849
Compound Name: AS-604850
Targets: PIK3CA|PIK3CG
MoA: PI3K inhibitor
SMILES: FC1(F)Oc2ccc(cc2O1)\C=C1/SC(=O)NC1=O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
33532 BRD-K63915849 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
33820 BRD-K63915849 A549 10 uM 24 h 0.0 0.0 0.0 0.38 1.35 1.72
34142 BRD-K63915849 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
34396 BRD-K63915849 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
34655 BRD-K63915849 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
34924 BRD-K63915849 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.37 -1.25 1.35
35174 BRD-K63915849 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
35382 BRD-K63915849 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
35594 BRD-K63915849 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
35814 BRD-K63915849 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
36094 BRD-K63915849 PC3 10 uM 6 h 0.0 0.0 0.0 -0.28 -0.94 0.39
36304 BRD-K63915849 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
36602 BRD-K63915849 SKB 10 uM 24 h 0.0 0.0 0.0 0.31 1.09 0.67
36846 BRD-K63915849 VCAP 10 uM 24 h -0.33 -1.38 1.08 -0.24 -0.82 0.15
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).