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CMap Candidate Details

Structure:
CMap ID: C04380
Pert ID: BRD-K43880410
Compound Name: pregnenolone
Targets: CYP17A1|SULT2B1
MoA: glutamate receptor modulator
SMILES: CC(=O)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
33660 BRD-K43880410 A375 10 uM 6 h -0.24 -1.0 0.15 -0.34 -1.15 1.06
33809 BRD-K43880410 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
34110 BRD-K43880410 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
34368 BRD-K43880410 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
34626 BRD-K43880410 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
35152 BRD-K43880410 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
35320 BRD-K43880410 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
35963 BRD-K43880410 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
36271 BRD-K43880410 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
36569 BRD-K43880410 SKB 10 uM 24 h -0.21 -0.88 0.03 0.0 0.0 0.0
36825 BRD-K43880410 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
52835 BRD-K43880410 HEPG2 20 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
53360 BRD-K43880410 MCF10A 30 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
91378 BRD-K43880410 HUH7 10 uM 72 h 0.0 0.0 0.0 -0.26 -0.88 0.25
99046 BRD-K43880410 NEU 10 uM 6 h -0.2 -0.83 0.0 -0.34 -1.15 1.08
99236 BRD-K43880410 NPC 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).