CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C04387
Pert ID:	BRD-A55913614
Compound Name:	primaquine
Targets:	KRT7\|NQO2
MoA:	antimalarial agent; DNA inhibitor
SMILES:	COc1cc(NC(C)CCCN)c2ncccc2c1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
5529	BRD-A55913614	HCC515	10 uM	24 h	0.29	1.2	0.43	0.0	0.0	0.0
5847	BRD-A55913614	HEPG2	10 uM	6 h	0.28	1.16	0.34	0.0	0.0	0.0
6441	BRD-A55913614	VCAP	10 uM	24 h	0.0	0.0	0.0	-0.34	-1.15	1.07
37521	BRD-A55913614	ASC	10 uM	24 h	0.0	0.0	0.0	-0.32	-1.07	0.75
38370	BRD-A55913614	NPC	10 uM	24 h	0.28	1.16	0.35	0.0	0.0	0.0
38874	BRD-A55913614	SKB	10 uM	24 h	0.34	1.42	1.08	0.0	0.0	0.0
91380	BRD-A55913614	HUH7	12.5 uM	72 h	0.0	0.0	0.0	-0.35	-1.18	1.14
100230	BRD-A55913614	U2OS	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
123784	BRD-A55913614	A375	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
123825	BRD-A55913614	A549	10 uM	24 h	0.19	0.79	0.0	0.33	1.16	0.9
123864	BRD-A55913614	HA1E	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
123882	BRD-A55913614	HEK293	0.04 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
123958	BRD-A55913614	HT29	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
123981	BRD-A55913614	JURKAT	0.37 uM	24 h	-0.26	-1.08	0.3	0.0	0.0	0.0
124037	BRD-A55913614	MCF10A	0.04 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
124087	BRD-A55913614	MCF??7.00	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
124113	BRD-A55913614	MDAMB231	0.125 uM	24 h	0.0	0.0	0.0	-0.26	-0.87	0.22
124149	BRD-A55913614	PC3	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
124164	BRD-A55913614	THP1	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
124217	BRD-A55913614	YAPC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
132185	BRD-A55913614	HELA	0.03 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0

Summary