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CMap Candidate Details

Structure:
CMap ID: C04394
Pert ID: BRD-K46317332
Compound Name: proadifen
Targets: NOS1
MoA: nitric oxide synthase inhibitor
SMILES: CCCC(C(=O)OCCN(CC)CC)(c1ccccc1)c1ccccc1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5208 BRD-K46317332 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
5456 BRD-K46317332 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
5638 BRD-K46317332 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
5921 BRD-K46317332 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6556 BRD-K46317332 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39329 BRD-K46317332 A549 10 uM 24 h 0.0 0.0 0.0 -0.23 -0.76 0.07
39704 BRD-K46317332 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
40282 BRD-K46317332 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40821 BRD-K46317332 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41125 BRD-K46317332 NPC 10 uM 24 h 0.0 0.0 0.0 -0.43 -1.44 15.35
41460 BRD-K46317332 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
51609 BRD-K46317332 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
51946 BRD-K46317332 PC3 10 uM 6 h 0.0 0.0 0.0 0.36 1.26 1.29
99566 BRD-K46317332 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).