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CMap Candidate Details

Structure:
CMap ID: C04401
Pert ID: BRD-K19352500
Compound Name: prochlorperazine
Targets: DRD1|DRD2|DRD3|DRD4
MoA: dopamine receptor antagonist
SMILES: CN1CCN(CCCN2c3ccccc3Sc3ccc(Cl)cc23)CC1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5307 BRD-K19352500 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
5591 BRD-K19352500 HCC515 10 uM 24 h 0.0 0.0 0.0 0.32 1.14 0.87
25338 BRD-K19352500 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37611 BRD-K19352500 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37879 BRD-K19352500 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.34 1.19 1.05
38062 BRD-K19352500 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
38441 BRD-K19352500 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38697 BRD-K19352500 PHH 10 uM 24 h 0.28 1.17 0.38 0.0 0.0 0.0
95510 BRD-K19352500 A549 10 uM 48 h 0.0 0.0 0.0 0.0 0.0 0.0
95703 BRD-K19352500 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
96738 BRD-K19352500 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
96789 BRD-K19352500 PC3 10 uM 24 h 0.0 0.0 0.0 0.27 0.97 0.35
120932 BRD-K19352500 HEK293 1.11 uM 24 h 0.26 1.1 0.24 0.25 0.89 0.21
120994 BRD-K19352500 HELA 10 uM 3 h 0.0 0.0 0.0 0.0 0.0 0.0
121028 BRD-K19352500 MCF??7.00 10 uM 24 h -0.25 -1.04 0.21 0.0 0.0 0.0
121090 BRD-K19352500 YAPC 0.125 uM 24 h 0.0 0.0 0.0 0.3 1.04 0.56
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).