CMap Candidate Details
Structure:
| CMap ID: | C04406 |
| Pert ID: | BRD-A16311756 |
| Compound Name: | profenamine |
| Targets: | CHRM1|CHRM2|GRIN3A |
| MoA: | butyrylcholinesterase inhibitor; cholinergic receptor antagonist |
| SMILES: | CCN(CC)C(C)CN1c2ccccc2Sc2ccccc12 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 6621 | BRD-A16311756 | A375 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 6917 | BRD-A16311756 | A549 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.27 | 0.95 | 0.32 |
| 7210 | BRD-A16311756 | HA1E | 10 uM | 24 h | -0.2 | -0.85 | 0.01 | 0.37 | 1.3 | 1.59 |
| 7511 | BRD-A16311756 | HCC515 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 7747 | BRD-A16311756 | HT29 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 8294 | BRD-A16311756 | PC3 | 10 uM | 24 h | 0.24 | 0.99 | 0.09 | -0.35 | -1.16 | 1.11 |
| 8553 | BRD-A16311756 | VCAP | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 52018 | BRD-A16311756 | MCF??7.00 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.34 | -1.14 | 1.02 |