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CMap Candidate Details

Structure:
CMap ID: C04413
Pert ID: BRD-K06980535
Compound Name: promazine
Targets: ADRA1A|ADRA1B|ADRA1D|CHRM1|CHRM2|CHRM3|CHRM4|CHRM5|DRD1|DRD2|DRD3|DRD4|HRH1|HTR2A|HTR2C
MoA: dopamine receptor antagonist
SMILES: CN(C)CCCN1c2ccccc2Sc2ccccc12
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5427 BRD-K06980535 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6159 BRD-K06980535 PC3 10 uM 24 h 0.0 0.0 0.0 0.24 0.85 0.15
6517 BRD-K06980535 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
8904 BRD-K06980535 A375 10 uM 24 h -0.24 -1.0 0.14 0.27 0.94 0.29
9170 BRD-K06980535 A549 10 uM 6 h -0.25 -1.05 0.23 0.0 0.0 0.0
9350 BRD-K06980535 AGS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9657 BRD-K06980535 H1299 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10144 BRD-K06980535 HCC515 10 uM 24 h 0.0 0.0 0.0 0.35 1.24 1.28
10453 BRD-K06980535 HCT116 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10938 BRD-K06980535 HT29 10 uM 24 h 0.0 0.0 0.0 0.24 0.85 0.14
11153 BRD-K06980535 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
11408 BRD-K06980535 NCIH2073 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11977 BRD-K06980535 NCIH596 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12258 BRD-K06980535 NOMO1 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12723 BRD-K06980535 SW480 10 uM 6 h 0.26 1.07 0.2 0.0 0.0 0.0
13202 BRD-K06980535 U937 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44839 BRD-K06980535 ASC 10 uM 24 h -0.31 -1.3 0.82 0.0 0.0 0.0
45147 BRD-K06980535 HEPG2 10 uM 6 h 0.22 0.93 0.05 0.26 0.91 0.24
45953 BRD-K06980535 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46273 BRD-K06980535 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46588 BRD-K06980535 SKB 10 uM 24 h 0.0 0.0 0.0 0.31 1.1 0.7
100017 BRD-K06980535 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).