CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C04418
Pert ID:	BRD-A26334849
Compound Name:	propafenone
Targets:	ADRB1\|ADRB2\|KCNA5\|KCNH2\|SCN5A
MoA:	antiarrhythmic
SMILES:	CCCNCC(O)COc1ccccc1C(=O)CCc1ccccc1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
4288	BRD-A26334849	HCC515	10 uM	24 h	-0.3	-1.25	0.7	-0.25	-0.84	0.17
4843	BRD-A26334849	VCAP	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
37332	BRD-A26334849	A549	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
37465	BRD-A26334849	ASC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
38137	BRD-A26334849	MCF??7.00	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
38315	BRD-A26334849	NPC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
90979	BRD-A26334849	HUH7	10 uM	72 h	0.0	0.0	0.0	0.0	0.0	0.0
119935	BRD-A26334849	A375	10 uM	24 h	0.28	1.16	0.36	0.0	0.0	0.0
120018	BRD-A26334849	HA1E	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
120043	BRD-A26334849	HELA	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
120090	BRD-A26334849	HT29	0.37 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
120208	BRD-A26334849	YAPC	10 uM	24 h	0.0	0.0	0.0	-0.29	-0.98	0.48
128841	BRD-A26334849	PC3	0.01 uM	24 h	0.26	1.08	0.22	-0.23	-0.78	0.1

Summary