CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C04426
Pert ID:	BRD-K82255054
Compound Name:	propofol
Targets:	FAAH\|GABRA1\|GABRA2\|GABRA3\|GABRA4\|GABRA5\|GABRA6\|GABRB1\|GABRB2\|GABRB3\|GABRD\|GABRE\|GABRG1\|GABRG2\|GABRG3\|GABRP\|GABRQ\|SCN2A\|SCN4A
MoA:	benzodiazepine receptor agonist
SMILES:	CC(C)c1cccc(C(C)C)c1O
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
4257	BRD-K82255054	HA1E	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
4496	BRD-K82255054	HCC515	10 uM	24 h	-0.22	-0.91	0.05	0.22	0.79	0.07
4826	BRD-K82255054	PC3	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
5130	BRD-K82255054	VCAP	10 uM	6 h	0.0	0.0	0.0	0.22	0.76	0.05
37193	BRD-K82255054	A375	10 uM	6 h	-0.27	-1.13	0.4	0.36	1.29	1.46
37414	BRD-K82255054	A549	10 uM	6 h	-0.2	-0.83	0.0	-0.3	-1.02	0.6
37747	BRD-K82255054	ASC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
37949	BRD-K82255054	HEPG2	10 uM	6 h	0.0	0.0	0.0	0.24	0.85	0.15
38110	BRD-K82255054	HT29	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
38224	BRD-K82255054	MCF??7.00	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
38562	BRD-K82255054	NPC	10 uM	24 h	0.2	0.82	0.0	0.25	0.88	0.18
39012	BRD-K82255054	SKB	10 uM	24 h	0.21	0.88	0.01	0.32	1.12	0.76
91176	BRD-K82255054	HUH7	20 uM	72 h	0.0	0.0	0.0	0.0	0.0	0.0

Summary