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CMap Candidate Details

Structure:
CMap ID: C04444
Pert ID: BRD-K77171813
Compound Name: proxyfan
Targets: HRH3
MoA: histamine receptor modulator
SMILES: C(COCc1ccccc1)Cc1cnc[nH]1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4140 BRD-K77171813 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4486 BRD-K77171813 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4822 BRD-K77171813 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
5125 BRD-K77171813 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44445 BRD-K77171813 A375 10 uM 6 h -0.29 -1.2 0.55 0.29 1.02 0.49
44727 BRD-K77171813 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45028 BRD-K77171813 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
45319 BRD-K77171813 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.44 1.54 2.31
45578 BRD-K77171813 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45847 BRD-K77171813 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 -0.36 -1.22 1.24
46141 BRD-K77171813 NPC 10 uM 24 h 0.0 0.0 0.0 -0.28 -0.96 0.43
46457 BRD-K77171813 PHH 10 uM 24 h 0.0 0.0 0.0 -0.2 -0.68 0.02
46781 BRD-K77171813 SKB 10 uM 24 h 0.0 0.0 0.0 -0.24 -0.79 0.11
99493 BRD-K77171813 U2OS 10 uM 6 h -0.17 -0.72 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).