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CMap Candidate Details

Structure:
CMap ID: C04454
Pert ID: BRD-K71266197
Compound Name: PSB-06126
Targets: ENTPD3
MoA: NTPDase inhibitor
SMILES: Nc1c2C(=O)c3ccccc3C(=O)c2c(Nc2cccc3ccccc23)cc1S(O)(=O)=O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5360 BRD-K71266197 HA1E 10 uM 24 h 0.0 0.0 0.0 0.3 1.08 0.65
5798 BRD-K71266197 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6111 BRD-K71266197 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6586 BRD-K71266197 VCAP 10 uM 6 h -0.26 -1.07 0.27 0.0 0.0 0.0
37409 BRD-K71266197 A549 10 uM 6 h 0.0 0.0 0.0 -0.28 -0.94 0.37
37728 BRD-K71266197 ASC 10 uM 24 h -0.2 -0.82 0.0 0.27 0.95 0.32
37940 BRD-K71266197 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
38104 BRD-K71266197 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
38546 BRD-K71266197 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38771 BRD-K71266197 PHH 10 uM 24 h 0.0 0.0 0.0 0.28 0.98 0.38
96365 BRD-K71266197 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
96436 BRD-K71266197 PC3 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
99416 BRD-K71266197 U2OS 10 uM 6 h 0.2 0.81 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).