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CMap Candidate Details

Structure:
CMap ID: C04455
Pert ID: BRD-K10177585
Compound Name: PSB-11
Targets: ADORA1|ADORA2A|ADORA3
MoA: adenosine receptor antagonist
SMILES: CC[C@@H]1CN2C(=N1)c1[nH]c(nc1N(C)C2=O)-c1ccccc1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1542 BRD-K10177585 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
1884 BRD-K10177585 HCC515 10 uM 24 h 0.23 0.95 0.06 0.0 0.0 0.0
2372 BRD-K10177585 PC3 10 uM 6 h 0.0 0.0 0.0 -0.32 -1.08 0.79
2535 BRD-K10177585 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41721 BRD-K10177585 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42059 BRD-K10177585 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42292 BRD-K10177585 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42625 BRD-K10177585 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42928 BRD-K10177585 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43290 BRD-K10177585 MCF??7.00 10 uM 6 h -0.23 -0.95 0.09 0.0 0.0 0.0
43485 BRD-K10177585 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43789 BRD-K10177585 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44066 BRD-K10177585 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
136402 BRD-K10177585 SHSY5Y 0.125 uM 24 h 0.0 0.0 0.0 0.4 1.41 2.19
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).