CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C04456
Pert ID:	BRD-K49027941
Compound Name:	PSB-1115
Targets:	ADORA1\|ADORA2B\|ADORA3
MoA:	adenosine receptor antagonist
SMILES:	CCCn1c(=O)[nH]c2nc([nH]c2c1=O)-c1ccc(cc1)S(O)(=O)=O
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
6764	BRD-K49027941	A375	10 uM	24 h	0.0	0.0	0.0	0.32	1.14	0.86
7004	BRD-K49027941	A549	10 uM	24 h	-0.21	-0.87	0.02	0.2	0.7	0.02
7331	BRD-K49027941	HA1E	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
7670	BRD-K49027941	HCC515	10 uM	6 h	0.24	1.02	0.13	-0.32	-1.07	0.76
8006	BRD-K49027941	HT29	10 uM	6 h	0.0	0.0	0.0	-0.21	-0.7	0.03
8101	BRD-K49027941	MCF??7.00	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
8378	BRD-K49027941	PC3	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
8690	BRD-K49027941	VCAP	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
99597	BRD-K49027941	U2OS	10 uM	6 h	-0.2	-0.82	0.0	0.28	0.98	0.37

Summary