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CMap Candidate Details

Structure:
CMap ID: C04464
Pert ID: BRD-K99092662
Compound Name: PS178990
Targets: AR
MoA: androgen receptor modulator
SMILES: Cc1c(ccc(C#N)c1Cl)N1C(=O)[C@@H]2[C@H](O)CCN2C1=O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
127751 BRD-K99092662 A375 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127796 BRD-K99092662 A549 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127829 BRD-K99092662 HA1E 0.37 uM 24 h 0.0 0.0 0.0 -0.33 -1.11 0.9
127879 BRD-K99092662 HEK293 0.125 uM 24 h 0.0 0.0 0.0 0.4 1.42 2.19
127953 BRD-K99092662 HUVEC 1.11 uM 24 h -0.32 -1.32 0.85 0.0 0.0 0.0
128005 BRD-K99092662 MCF10A 3.33 uM 24 h -0.21 -0.88 0.03 -0.29 -0.97 0.46
128086 BRD-K99092662 YAPC 1.11 uM 24 h -0.26 -1.07 0.27 0.0 0.0 0.0
135580 BRD-K99092662 HELA 0.25 uM 24 h -0.25 -1.06 0.25 0.0 0.0 0.0
135622 BRD-K99092662 HT29 0.01 uM 24 h 0.34 1.42 1.1 0.0 0.0 0.0
135671 BRD-K99092662 JURKAT 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135703 BRD-K99092662 MCF??7.00 0.25 uM 24 h 0.0 0.0 0.0 -0.26 -0.87 0.24
135726 BRD-K99092662 PC3 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).