CMap Candidate Details
Structure:
| CMap ID: | C04472 |
| Pert ID: | BRD-A28970875 |
| Compound Name: | puromycin |
| Targets: | NHP2L1|RPL10L|RPL11|RPL13A|RPL15|RPL19|RPL23|RPL23A|RPL26L1|RPL3|RPL37|RPL8|RSL24D1 |
| MoA: | protein synthesis inhibitor |
| SMILES: | COc1ccc(C[C@H](N)C(=O)N[C@@H]2[C@@H](CO)OC([C@@H]2O)n2cnc3c(ncnc23)N(C)C)cc1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 2962 | BRD-A28970875 | HA1E | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.48 | -1.6 | 15.65 |
| 3314 | BRD-A28970875 | HCC515 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 3432 | BRD-A28970875 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 3675 | BRD-A28970875 | VCAP | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.25 | -0.85 | 0.2 |
| 44238 | BRD-A28970875 | A375 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 44639 | BRD-A28970875 | A549 | 10 uM | 6 h | 0.2 | 0.85 | 0.01 | -0.45 | -1.53 | 15.35 |
| 44755 | BRD-A28970875 | ASC | 10 uM | 24 h | 0.18 | 0.74 | 0.0 | 0.35 | 1.25 | 1.29 |
| 45076 | BRD-A28970875 | HEPG2 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.43 | -1.43 | 15.35 |
| 45355 | BRD-A28970875 | HT29 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 45739 | BRD-A28970875 | MCF??7.00 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 46188 | BRD-A28970875 | PHH | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 46505 | BRD-A28970875 | SKB | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.29 | 1.02 | 0.47 |