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CMap Candidate Details

Structure:
CMap ID: C04483
Pert ID: BRD-K28667793
Compound Name: pyrazinamide
Targets: FASN
MoA: fatty acid synthase inhibitor
SMILES: NC(=O)c1cnccn1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
50350 BRD-K28667793 HCC515 10 uM 6 h 0.0 0.0 0.0 0.31 1.09 0.67
52908 BRD-K28667793 HEPG2 40 uM 24 h 0.29 1.2 0.43 0.0 0.0 0.0
53186 BRD-K28667793 MCF10A 100 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
119947 BRD-K28667793 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
119989 BRD-K28667793 A549 3.33 uM 24 h 0.0 0.0 0.0 -0.25 -0.85 0.19
120027 BRD-K28667793 HA1E 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120053 BRD-K28667793 HELA 0.125 uM 24 h -0.29 -1.23 0.62 -0.26 -0.89 0.27
120106 BRD-K28667793 HT29 3.33 uM 24 h -0.19 -0.78 0.0 0.0 0.0 0.0
120148 BRD-K28667793 MCF??7.00 1.11 uM 24 h 0.27 1.13 0.3 0.0 0.0 0.0
128848 BRD-K28667793 PC3 0.74 uM 24 h 0.0 0.0 0.0 -0.31 -1.06 0.73
128871 BRD-K28667793 YAPC 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).