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CMap Candidate Details

Structure:
CMap ID: C04484
Pert ID: BRD-K61693562
Compound Name: pyrazinoylguanidine
Targets:
MoA: diuretic
SMILES: NC(=N)NC(=O)c1cnccn1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
124631 BRD-K61693562 HA1E 0.125 uM 24 h 0.2 0.84 0.0 0.0 0.0 0.0
124818 BRD-K61693562 MDAMB231 10 uM 24 h 0.25 1.04 0.15 0.0 0.0 0.0
124861 BRD-K61693562 PC3 0.125 uM 24 h 0.0 0.0 0.0 0.36 1.29 1.43
124901 BRD-K61693562 THP1 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124924 BRD-K61693562 YAPC 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132674 BRD-K61693562 A375 0.01 uM 24 h 0.24 1.02 0.13 0.0 0.0 0.0
132707 BRD-K61693562 A549 0.01 uM 24 h 0.0 0.0 0.0 0.26 0.92 0.25
132775 BRD-K61693562 HEK293 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132800 BRD-K61693562 HELA 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132819 BRD-K61693562 HT29 0.25 uM 24 h 0.0 0.0 0.0 -0.28 -0.95 0.4
132849 BRD-K61693562 JURKAT 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132889 BRD-K61693562 MCF10A 2.22 uM 24 h 0.0 0.0 0.0 0.23 0.83 0.11
132914 BRD-K61693562 MCF??7.00 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).