Logo 1 Logo 2

CMap Candidate Details

Structure:
CMap ID: C04499
Pert ID: BRD-K80970344
Compound Name: pyrrolidine-dithiocarbamate
Targets: HSD11B1|RELA
MoA: NFkB pathway inhibitor
SMILES: SC(=S)N1CCCC1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1781 BRD-K80970344 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
1979 BRD-K80970344 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2425 BRD-K80970344 PC3 10 uM 6 h 0.25 1.05 0.17 -0.27 -0.9 0.29
2686 BRD-K80970344 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39189 BRD-K80970344 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39497 BRD-K80970344 A549 10 uM 6 h 0.26 1.07 0.19 -0.31 -1.03 0.62
39779 BRD-K80970344 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
40072 BRD-K80970344 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40336 BRD-K80970344 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40512 BRD-K80970344 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.42 -1.4 2.02
40879 BRD-K80970344 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41198 BRD-K80970344 NPC 10 uM 24 h 0.23 0.97 0.08 -0.39 -1.3 1.6
41537 BRD-K80970344 SKB 10 uM 24 h 0.0 0.0 0.0 -0.38 -1.27 1.39
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).