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CMap Candidate Details

Structure:
CMap ID: C00045
Pert ID: BRD-K93176058
Compound Name: AC-55649
Targets: RARA|RARB
MoA: retinoid receptor agonist
SMILES: CCCCCCCCc1ccc(cc1)-c1ccc(cc1)C(O)=O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
9549 BRD-K93176058 AGS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9857 BRD-K93176058 H1299 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10116 BRD-K93176058 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
10631 BRD-K93176058 HCT116 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11617 BRD-K93176058 NCIH2073 10 uM 6 h 0.37 1.53 1.45 0.0 0.0 0.0
11874 BRD-K93176058 NCIH508 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12174 BRD-K93176058 NCIH596 10 uM 6 h 0.0 0.0 0.0 0.32 1.12 0.78
12906 BRD-K93176058 SW480 10 uM 6 h 0.0 0.0 0.0 0.31 1.08 0.66
12930 BRD-K93176058 THP1 10 uM 6 h -0.26 -1.09 0.32 0.0 0.0 0.0
13518 BRD-K93176058 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
117347 BRD-K93176058 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
117385 BRD-K93176058 A549 10 uM 24 h -0.24 -1.01 0.17 0.0 0.0 0.0
117425 BRD-K93176058 HA1E 0.04 uM 24 h 0.0 0.0 0.0 -0.41 -1.37 2.02
117518 BRD-K93176058 HEPG2 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
117561 BRD-K93176058 HT29 10 uM 24 h -0.22 -0.92 0.06 -0.36 -1.2 1.16
117601 BRD-K93176058 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
117638 BRD-K93176058 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).