CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C04508
Pert ID:	BRD-K97399794
Compound Name:	quercetin
Targets:	ATP5A1\|ATP5B\|ATP5C1\|HCK\|HIBCH\|PIK3CG\|PIM1\|STK17B\|UGT3A1
MoA:	polar auxin transport inhibitor
SMILES:	Oc1cc(O)c2c(c1)oc(-c1ccc(O)c(O)c1)c(O)c2=O
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
2953	BRD-K97399794	HA1E	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
3416	BRD-K97399794	HCC515	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
3576	BRD-K97399794	PC3	10 uM	24 h	-0.3	-1.23	0.63	0.0	0.0	0.0
3911	BRD-K97399794	VCAP	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
44466	BRD-K97399794	A375	10 uM	6 h	0.0	0.0	0.0	-0.33	-1.11	0.91
45059	BRD-K97399794	ASC	10 uM	24 h	0.0	0.0	0.0	0.3	1.05	0.58
45729	BRD-K97399794	MCF??7.00	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
46168	BRD-K97399794	NPC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
46483	BRD-K97399794	PHH	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
46813	BRD-K97399794	SKB	10 uM	24 h	0.0	0.0	0.0	-0.38	-1.29	1.53
99112	BRD-K97399794	NEU	10 uM	6 h	0.0	0.0	0.0	0.28	0.98	0.36
119654	BRD-K97399794	HEPG2	10 uM	24 h	0.0	0.0	0.0	-0.29	-0.98	0.47
128403	BRD-K97399794	A549	1.11 uM	24 h	-0.2	-0.85	0.01	0.0	0.0	0.0
128464	BRD-K97399794	HEK293	10 uM	24 h	0.25	1.03	0.14	-0.28	-0.93	0.35
128488	BRD-K97399794	HELA	10 uM	24 h	0.26	1.1	0.24	-0.28	-0.96	0.43
128519	BRD-K97399794	HT29	1.11 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
128574	BRD-K97399794	JURKAT	1.11 uM	24 h	0.0	0.0	0.0	0.19	0.69	0.01
128666	BRD-K97399794	MDAMB231	1.11 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
128745	BRD-K97399794	THP1	0.125 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
128784	BRD-K97399794	YAPC	1.11 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
136324	BRD-K97399794	MCF10A	0.25 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0

Summary