CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C04510
Pert ID:	BRD-K39503511
Compound Name:	quiflapon
Targets:	ALOX5\|ALOX5AP
MoA:	leukotriene synthesis inhibitor
SMILES:	CC(C)(C)Sc1c(CC(C)(C)C(O)=O)n(Cc2ccc(Cl)cc2)c2ccc(OCc3ccc4ccccc4n3)cc12
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
8939	BRD-K39503511	A375	80 uM	24 h	0.0	0.0	0.0	-0.37	-1.26	1.35
9099	BRD-K39503511	A549	80 uM	24 h	0.0	0.0	0.0	-0.36	-1.21	1.23
9419	BRD-K39503511	AGS	80 uM	6 h	-0.27	-1.13	0.4	0.0	0.0	0.0
9726	BRD-K39503511	H1299	80 uM	6 h	0.25	1.06	0.18	-0.38	-1.27	1.39
10055	BRD-K39503511	HA1E	80 uM	6 h	-0.28	-1.15	0.43	-0.45	-1.51	15.35
10357	BRD-K39503511	HCC515	80 uM	6 h	-0.21	-0.88	0.03	0.0	0.0	0.0
10512	BRD-K39503511	HCT116	80 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
10781	BRD-K39503511	HEPG2	80 uM	6 h	0.0	0.0	0.0	-0.45	-1.52	15.35
10973	BRD-K39503511	HT29	80 uM	24 h	0.29	1.23	0.5	-0.31	-1.04	0.65
11237	BRD-K39503511	MCF??7.00	80 uM	24 h	0.0	0.0	0.0	-0.31	-1.05	0.7
11482	BRD-K39503511	NCIH2073	80 uM	6 h	-0.28	-1.16	0.45	-0.26	-0.86	0.22
11760	BRD-K39503511	NCIH508	80 uM	6 h	-0.21	-0.88	0.03	0.39	1.38	2.16
12046	BRD-K39503511	NCIH596	80 uM	6 h	0.0	0.0	0.0	-0.25	-0.85	0.19
12311	BRD-K39503511	NOMO1	80 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
12563	BRD-K39503511	PC3	80 uM	24 h	0.21	0.88	0.02	0.0	0.0	0.0
12787	BRD-K39503511	SW480	80 uM	6 h	0.0	0.0	0.0	-0.35	-1.19	1.16
13100	BRD-K39503511	THP1	80 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
13268	BRD-K39503511	U937	80 uM	6 h	0.0	0.0	0.0	0.22	0.79	0.07
13618	BRD-K39503511	VCAP	80 uM	6 h	0.0	0.0	0.0	0.34	1.19	1.02
123594	BRD-K39503511	HEK293	0.125 uM	24 h	0.0	0.0	0.0	-0.33	-1.11	0.92
123629	BRD-K39503511	HELA	10 uM	24 h	0.17	0.71	0.0	0.0	0.0	0.0
123709	BRD-K39503511	MCF10A	10 uM	24 h	0.0	0.0	0.0	-0.38	-1.26	1.38
123775	BRD-K39503511	YAPC	3.33 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0

Summary