CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C04512
Pert ID:	BRD-K72222507
Compound Name:	quinapril
Targets:	ACE
MoA:	angiotensin converting enzyme inhibitor
SMILES:	CCOC(=O)[C@H](CCc1ccccc1)N[C@@H](C)C(=O)N1Cc2ccccc2C[C@H]1C(O)=O
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
5681	BRD-K72222507	HCC515	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
6361	BRD-K72222507	VCAP	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
52815	BRD-K72222507	HEPG2	0.66 uM	24 h	0.0	0.0	0.0	0.23	0.82	0.1
91407	BRD-K72222507	HUH7	8 uM	72 h	0.0	0.0	0.0	0.0	0.0	0.0
99429	BRD-K72222507	U2OS	10 uM	6 h	0.0	0.0	0.0	-0.22	-0.75	0.06
126380	BRD-K72222507	A549	1.11 uM	24 h	-0.27	-1.1	0.36	-0.34	-1.15	1.07
126439	BRD-K72222507	HEK293	3.33 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
126556	BRD-K72222507	MDAMB231	0.37 uM	24 h	0.18	0.74	0.0	0.0	0.0	0.0
126578	BRD-K72222507	PC3	0.37 uM	24 h	0.0	0.0	0.0	0.33	1.18	0.97
134349	BRD-K72222507	A375	0.01 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
134400	BRD-K72222507	HA1E	0.74 uM	24 h	0.0	0.0	0.0	0.38	1.33	1.72
134428	BRD-K72222507	HELA	0.08 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
134464	BRD-K72222507	HT29	0.25 uM	24 h	0.0	0.0	0.0	-0.37	-1.26	1.35
134505	BRD-K72222507	HUVEC	0.03 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
134540	BRD-K72222507	MCF10A	0.08 uM	24 h	0.23	0.96	0.07	0.0	0.0	0.0
134568	BRD-K72222507	MCF??7.00	0.08 uM	24 h	0.0	0.0	0.0	0.28	0.98	0.37
134652	BRD-K72222507	YAPC	0.25 uM	24 h	0.22	0.94	0.05	0.0	0.0	0.0

Summary