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CMap Candidate Details

Structure:
CMap ID: C04521
Pert ID: BRD-K26548821
Compound Name: quinpirol-(-)
Targets: DRD1|DRD2|DRD3|DRD4|HTR1A|HTR2A|HTR2B|HTR2C
MoA: dopamine receptor agonist
SMILES: CCCN1CCC[C@@H]2Cc3n[nH]cc3C[C@@H]12
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
3002 BRD-K26548821 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
3350 BRD-K26548821 HCC515 10 uM 6 h 0.0 0.0 0.0 -0.25 -0.84 0.18
3608 BRD-K26548821 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
3761 BRD-K26548821 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44352 BRD-K26548821 A375 10 uM 6 h 0.0 0.0 0.0 0.2 0.72 0.02
44688 BRD-K26548821 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44910 BRD-K26548821 ASC 10 uM 24 h -0.16 -0.67 0.0 -0.27 -0.92 0.34
45214 BRD-K26548821 HEPG2 10 uM 6 h 0.23 0.97 0.08 0.19 0.69 0.01
45480 BRD-K26548821 HT29 10 uM 6 h -0.25 -1.05 0.24 0.0 0.0 0.0
45798 BRD-K26548821 MCF??7.00 10 uM 6 h -0.19 -0.79 0.0 -0.25 -0.83 0.16
46029 BRD-K26548821 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46663 BRD-K26548821 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
91114 BRD-K26548821 HUH7 15 uM 72 h -0.21 -0.86 0.01 -0.23 -0.76 0.08
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).