CMap Candidate Details
Structure:
| CMap ID: | C04525 |
| Pert ID: | BRD-K56596464 |
| Compound Name: | QX-314 |
| Targets: | MAPK14|TGFBR1 |
| MoA: | sodium channel blocker |
| SMILES: | CC[N+](CC)(CC)CC(=O)Nc1c(C)cccc1C |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 3041 | BRD-K56596464 | HA1E | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.2 | -0.67 | 0.02 |
| 3238 | BRD-K56596464 | HCC515 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 3635 | BRD-K56596464 | PC3 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 3836 | BRD-K56596464 | VCAP | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 44420 | BRD-K56596464 | A375 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 44598 | BRD-K56596464 | A549 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 44991 | BRD-K56596464 | ASC | 10 uM | 24 h | -0.22 | -0.91 | 0.05 | -0.34 | -1.15 | 1.06 |
| 45283 | BRD-K56596464 | HEPG2 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.24 | -0.8 | 0.12 |
| 45548 | BRD-K56596464 | HT29 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.29 | -0.97 | 0.46 |
| 45707 | BRD-K56596464 | MCF??7.00 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 46107 | BRD-K56596464 | NPC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.31 | 1.08 | 0.66 |
| 46420 | BRD-K56596464 | PHH | 10 uM | 24 h | 0.24 | 1.0 | 0.11 | 0.0 | 0.0 | 0.0 |
| 46746 | BRD-K56596464 | SKB | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 99684 | BRD-K56596464 | U2OS | 15 uM | 6 h | -0.21 | -0.87 | 0.02 | 0.0 | 0.0 | 0.0 |