CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C04536
Pert ID:	BRD-K04111260
Compound Name:	raclopride
Targets:	DRD2\|DRD3\|HTR1A
MoA:	dopamine receptor antagonist
SMILES:	CCN1CCC[C@H]1CNC(=O)c1c(O)c(Cl)cc(Cl)c1OC
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
3130	BRD-K04111260	HCC515	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
3936	BRD-K04111260	VCAP	10 uM	6 h	0.0	0.0	0.0	-0.28	-0.95	0.4
39422	BRD-K04111260	A549	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
39619	BRD-K04111260	ASC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
39939	BRD-K04111260	HEPG2	10 uM	6 h	-0.19	-0.8	0.0	0.0	0.0	0.0
40743	BRD-K04111260	NEU	10 uM	24 h	-0.27	-1.11	0.37	0.0	0.0	0.0
41043	BRD-K04111260	NPC	10 uM	24 h	0.0	0.0	0.0	0.23	0.81	0.08
41370	BRD-K04111260	SKB	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
51582	BRD-K04111260	MCF??7.00	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
51796	BRD-K04111260	PC3	10 uM	24 h	0.0	0.0	0.0	-0.32	-1.07	0.76
90954	BRD-K04111260	HUH7	10 uM	72 h	0.0	0.0	0.0	0.0	0.0	0.0
99987	BRD-K04111260	U2OS	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
122616	BRD-K04111260	HEK293	0.04 uM	24 h	-0.23	-0.95	0.09	0.0	0.0	0.0
122695	BRD-K04111260	MCF10A	3.33 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
130856	BRD-K04111260	A375	2.22 uM	24 h	0.0	0.0	0.0	-0.25	-0.84	0.18
130897	BRD-K04111260	HA1E	0.25 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
130948	BRD-K04111260	HELA	0.08 uM	24 h	0.0	0.0	0.0	0.31	1.1	0.7
130986	BRD-K04111260	HT29	0.01 uM	24 h	0.0	0.0	0.0	0.3	1.07	0.63
131016	BRD-K04111260	HUVEC	0.01 uM	24 h	-0.25	-1.04	0.21	0.0	0.0	0.0
131102	BRD-K04111260	MDAMB231	0.08 uM	24 h	0.23	0.96	0.07	-0.42	-1.4	2.02
131165	BRD-K04111260	YAPC	0.74 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0

Summary