CMap Candidate Details
Structure:
| CMap ID: | C04544 |
| Pert ID: | BRD-K08586861 |
| Compound Name: | ramatroban |
| Targets: | PTGDR2|TBXA2R |
| MoA: | prostanoid receptor antagonist |
| SMILES: | OC(=O)CCn1c2CC[C@H](Cc2c2ccccc12)NS(=O)(=O)c1ccc(F)cc1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 121144 | BRD-K08586861 | A375 | 1.11 uM | 24 h | 0.23 | 0.95 | 0.06 | 0.28 | 1.01 | 0.44 |
| 121181 | BRD-K08586861 | A549 | 0.04 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121217 | BRD-K08586861 | HA1E | 0.37 uM | 24 h | 0.29 | 1.23 | 0.49 | 0.0 | 0.0 | 0.0 |
| 121287 | BRD-K08586861 | MCF??7.00 | 0.37 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121307 | BRD-K08586861 | PC3 | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129260 | BRD-K08586861 | HELA | 0.01 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129291 | BRD-K08586861 | HT29 | 0.25 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.28 | -0.95 | 0.4 |
| 129365 | BRD-K08586861 | YAPC | 0.03 uM | 24 h | -0.24 | -1.01 | 0.16 | -0.29 | -0.97 | 0.45 |